Sequential modeling for a class of reference‐based imputation methods in clinical trials with quantitative or binary outcomes
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DOI: 10.1002/sim.9303
Abstract: We consider treatment effect estimation in a randomized clinical trial with longitudinally measured quantitative or categorical outcomes. To handle missing data, we usually assume missing at random and then conduct sensitivity analysis for missing not… read more here.
Keywords: reference; imputation methods; reference based; treatment ... See more keywords
Characterizing the effects of missing data and evaluating imputation methods for chemical prioritization applications using ToxPi
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DOI: 10.1186/s13040-018-0169-5
Abstract: BackgroundThe Toxicological Priority Index (ToxPi) is a method for prioritization and profiling of chemicals that integrates data from diverse sources. However, individual data sources (“assays”), such as in vitro bioassays or in vivo study endpoints,… read more here.
Keywords: imputation; effects missing; prioritization; characterizing effects ... See more keywords
Assessment of the performance of different imputation methods for low-coverage sequencing in Holstein cattle.
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DOI: 10.3168/jds.2021-21360
Abstract: Low-coverage sequencing (LCS) followed by imputation has been proposed as a cost-effective genotyping approach for obtaining genotypes of whole-genome variants. Imputation performance is essential for the effectiveness of this approach. Several imputation methods have been… read more here.
Keywords: imputation methods; coverage sequencing; holstein cattle; low coverage ... See more keywords
Empirical Comparison of Imputation Methods for Multivariate Missing Data in Public Health
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DOI: 10.3390/ijerph20021524
Abstract: Sample estimates derived from data with missing values may be unreliable and may negatively impact the inferences that researchers make about the underlying population due to nonresponse bias. As a result, imputation is often preferred… read more here.
Keywords: imputation methods; health; public health; missing data ... See more keywords