Cross protection by inactivated recombinant influenza viruses containing chimeric hemagglutinin conjugates with a conserved neuraminidase or M2 ectodomain epitope.
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DOI: 10.1016/j.virol.2020.08.003
Abstract: Influenza virus neuraminidase (NA) contains a universally conserved epitope (NAe, NA222-230). However, no studies have reported vaccines targeting this NA conserved epitope and inducing antibodies recognizing NAe. The extracellular domain of M2 (M2e) is considered… read more here.
Keywords: m2e; inactivated recombinant; recombinant influenza; epitope ... See more keywords