Articles with "inactivating alterations" as a keyword



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Abstract LB288: Biomarker analysis from AMPECT correlating response to nab-sirolimus with TSC1 and TSC2 inactivating alterations

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Published in 2023 at "Cancer Research"

DOI: 10.1158/1538-7445.am2023-lb288

Abstract: nab-Sirolimus is an mTOR inhibitor (mTORi) approved in the US for the treatment of adult patients with locally advanced, unresectable, or metastatic malignant perivascular epithelioid cell tumor (PEComa) based on clinical efficacy and safety data… read more here.

Keywords: inactivating alterations; tsc2 inactivating; tsc1 tsc2; nab sirolimus ... See more keywords