Inactivating histone deacetylase HDA promotes longevity by mobilizing trehalose metabolism
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DOI: 10.1038/s41467-021-22257-2
Abstract: Histone acetylations are important epigenetic markers for transcriptional activation in response to metabolic changes and various stresses. Using the high-throughput SEquencing-Based Yeast replicative Lifespan screen method and the yeast knockout collection, we demonstrate that the… read more here.
Keywords: longevity; hda; histone deacetylase; histone ... See more keywords