Structural Characterization of KOR Inactive and Active States for 3D Pharmacology and Drug Discovery.
Sign Up to like & getrecommendations! Published in 2021 at "Handbook of experimental pharmacology"
DOI: 10.1007/164_2021_461
Abstract: The structure of the human kappa opioid receptor (KOR) in complex with the long-acting antagonist JDTic was solved crystallographically in 2012 and, along with structures of other opioid receptors, revolutionized our understanding of opioid system… read more here.
Keywords: kor inactive; characterization kor; pharmacology; active states ... See more keywords
Differentiating between Inactive and Active States of Rhodopsin by Atomic Force Microscopy in Native Membranes.
Sign Up to like & getrecommendations! Published in 2019 at "Analytical chemistry"
DOI: 10.1021/acs.analchem.9b00546
Abstract: Membrane proteins, including G protein-coupled receptors (GPCRs), present a challenge in studying their structural properties under physiological conditions. Moreover, to better understand the activity of proteins requires examination of single molecule behaviors rather than ensemble… read more here.
Keywords: state; microscopy; active states; inactive active ... See more keywords
Adolescents’ Experiences and Perspectives on Physical Activity and Friend Influences Over Time
Sign Up to like & getrecommendations! Published in 2020 at "Research Quarterly for Exercise and Sport"
DOI: 10.1080/02701367.2020.1739607
Abstract: ABSTRACT Purpose: Understanding friend influences on adolescents’ PA, and how these change over time, is fundamental to developing interventions for promoting active lifestyles yet the latter in particular remains unexplored. This study explored the experiences… read more here.
Keywords: adolescents experiences; time; friend influences; experiences perspectives ... See more keywords
The Penetration–Explosion Effects of Differently Distributed Inactive/Active Composite Shaped Charge Jets
Sign Up to like & getrecommendations! Published in 2022 at "Materials"
DOI: 10.3390/ma15010344
Abstract: An analysis of the penetration–explosion (PE) effects of four distributions of inactive/active composite jets shows that a well-designed inactive/active double-layer liner can promote composite jet damage. Penetration experiments were then carried out for shaped charge… read more here.
Keywords: penetration explosion; explosion effects; inactive active; shaped charge ... See more keywords