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   Articles with "inactive active" as a keyword



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Structural Characterization of KOR Inactive and Active States for 3D Pharmacology and Drug Discovery.

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recommendations! Published in 2021 at "Handbook of experimental pharmacology"

DOI: 10.1007/164_2021_461

Abstract: The structure of the human kappa opioid receptor (KOR) in complex with the long-acting antagonist JDTic was solved crystallographically in 2012 and, along with structures of other opioid receptors, revolutionized our understanding of opioid system… read more here.

Keywords: kor inactive; characterization kor; pharmacology; active states ... See more keywords

Formation of long-lasting inactive and active multiple tropical cyclone events in the western North Pacific

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recommendations! Published in 2024 at "Climate Dynamics"

DOI: 10.1007/s00382-024-07101-9

Abstract: Long-lasting inactive and active multiple tropical cyclone (MTC) events in the western North Pacific (WNP) during July–August 1982–2020 were investigated. It is found that the significant difference between the inactive and active events lies on… read more here.

Keywords: long lasting; active multiple; tropical cyclone; lasting inactive ... See more keywords

Differentiating between Inactive and Active States of Rhodopsin by Atomic Force Microscopy in Native Membranes.

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recommendations! Published in 2019 at "Analytical chemistry"

DOI: 10.1021/acs.analchem.9b00546

Abstract: Membrane proteins, including G protein-coupled receptors (GPCRs), present a challenge in studying their structural properties under physiological conditions. Moreover, to better understand the activity of proteins requires examination of single molecule behaviors rather than ensemble… read more here.

Keywords: state; microscopy; active states; inactive active ... See more keywords

Structural Insight into the Inactive/Active States of 5-HT1AR and Molecular Mechanisms of Electric Fields in Modulating 5-HT1AR

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recommendations! Published in 2025 at "Journal of chemical information and modeling"

DOI: 10.1021/acs.jcim.4c02278

Abstract: Probing the differences between inactive/active states of the serotonin 1A receptor (5-HT1AR) and the dynamic receptor conformations is vital for understanding signaling transduction pathways and diverse physiological responses. Here, we compared the conformational features between… read more here.

Keywords: states ht1ar; modulating ht1ar; active states; electric fields ... See more keywords
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Adolescents’ Experiences and Perspectives on Physical Activity and Friend Influences Over Time

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recommendations! Published in 2020 at "Research Quarterly for Exercise and Sport"

DOI: 10.1080/02701367.2020.1739607

Abstract: ABSTRACT Purpose: Understanding friend influences on adolescents’ PA, and how these change over time, is fundamental to developing interventions for promoting active lifestyles yet the latter in particular remains unexplored. This study explored the experiences… read more here.

Keywords: adolescents experiences; time; friend influences; experiences perspectives ... See more keywords

Identifying and controlling inactive and active conformations of a serine protease

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recommendations! Published in 2025 at "Science Advances"

DOI: 10.1126/sciadv.adu7447

Abstract: Serine proteases have been proposed to dynamically sample inactive and active conformations, but direct evidence at atomic resolution has remained elusive. Using nuclear magnetic resonance (NMR), we identified a single residue, D164, in exfoliative toxin… read more here.

Keywords: conformations serine; controlling inactive; inactive active; identifying controlling ... See more keywords

The Penetration–Explosion Effects of Differently Distributed Inactive/Active Composite Shaped Charge Jets

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recommendations! Published in 2022 at "Materials"

DOI: 10.3390/ma15010344

Abstract: An analysis of the penetration–explosion (PE) effects of four distributions of inactive/active composite jets shows that a well-designed inactive/active double-layer liner can promote composite jet damage. Penetration experiments were then carried out for shaped charge… read more here.

Keywords: penetration explosion; explosion effects; inactive active; shaped charge ... See more keywords