Trans- and cis-acting effects of Firre on epigenetic features of the inactive X chromosome
Sign Up to like & getrecommendations! Published in 2020 at "Nature Communications"
DOI: 10.1038/s41467-020-19879-3
Abstract: Firre encodes a lncRNA involved in nuclear organization. Here, we show that Firre RNA expressed from the active X chromosome maintains histone H3K27me3 enrichment on the inactive X chromosome (Xi) in somatic cells. This trans-acting… read more here.
Keywords: trans cis; inactive chromosome; firre rna; cis acting ... See more keywords
Structural aspects of the inactive X chromosome
Sign Up to like & getrecommendations! Published in 2017 at "Philosophical Transactions of the Royal Society B: Biological Sciences"
DOI: 10.1098/rstb.2016.0357
Abstract: A striking difference between male and female nuclei was recognized early on by the presence of a condensed chromatin body only in female cells. Mary Lyon proposed that X inactivation or silencing of one X… read more here.
Keywords: microscopy; inactive chromosome; inactivation; structural aspects ... See more keywords