Articles with "inactive ingredients" as a keyword



Shedding light on interaction of so called inactive ingredients (excipients) with permeability-glycoprotein

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Published in 2019 at "Journal of Drug Delivery Science and Technology"

DOI: 10.1016/j.jddst.2019.05.022

Abstract: Abstract Permeability glycoprotein (P-gp) is a 170 kDa membrane transporter from the category of efflux pumps, which is situated at the apical site of epithelial membrane. P-gp is known to efflux diverse classes of chemical compounds… read more here.

Keywords: shedding light; drug; permeability glycoprotein; inactive ingredients ... See more keywords

Biological activities of drug inactive ingredients

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Published in 2022 at "Briefings in bioinformatics"

DOI: 10.1093/bib/bbac160

Abstract: In a drug formulation (DFM), the major components by mass are not Active Pharmaceutical Ingredient (API) but rather Drug Inactive Ingredients (DIGs). DIGs can reach much higher concentrations than that achieved by API, which raises… read more here.

Keywords: drug inactive; activities digs; activities drug; inactive ingredients ... See more keywords

Contact Allergens in Prescription Topical Ophthalmic Medications

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Published in 2021 at "Dermatitis"

DOI: 10.1097/der.0000000000000751

Abstract: Background/Objective Both active and inactive ingredients in topical ophthalmic agents may cause allergic contact dermatitis. Here, we examined ingredients in prescription topical ophthalmic medications available in the United States. Methods A comprehensive list of topical… read more here.

Keywords: topical ophthalmic; ophthalmic medications; acds core; inactive ingredients ... See more keywords

Occurrence frequency of inactive ingredients in biological formulations.

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Published in 2020 at "PLOS ONE"

DOI: 10.1371/journal.pone.0235076.s004

Abstract: List of all ingredients that occur in biological formulations. Percentage occurrence refers to the fraction of all biological formulations analyzed that contain the ingredient. (PDF) read more here.

Keywords: inactive ingredients; frequency inactive; occurrence frequency; biological formulations ... See more keywords