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Inadequate brain glycogen or sleep increases spreading depression susceptibility

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0 Published in 2018 at "Annals of Neurology"

DOI: 10.1002/ana.25122

Abstract: Glycogen in astrocyte processes contributes to maintenance of low extracellular glutamate and K+ concentrations around excitatory synapses. Sleep deprivation (SD), a common migraine trigger, induces transcriptional changes in astrocytes, reducing glycogen breakdown. We hypothesize that… read more here.

Keywords: brain glycogen; sleep increases; glycogen sleep; glycogen ... See more keywords