Ratpost: a searchable database of protein-inactivating sequence variations in 40 sequenced rat-inbred strains
Sign Up to like & getrecommendations! Published in 2021 at "Mammalian Genome"
DOI: 10.1007/s00335-020-09853-1
Abstract: Rat-inbred strains are essential as scientific tools. We have analyzed the publicly available genome sequences of 40 rat-inbred strains and provide an overview of sequence variations leading to amino acid changes in protein-coding genes, premature… read more here.
Keywords: protein; inbred strains; rat inbred; sequence variations ... See more keywords
No effect of prenatal vitamin D deficiency on autism-relevant behaviours in multiple inbred strains of mice
Sign Up to like & getrecommendations! Published in 2018 at "Behavioural Brain Research"
DOI: 10.1016/j.bbr.2018.04.004
Abstract: Abstract Autism Spectrum Disorders (ASD) is a group of neurodevelopmental disorders commonly characterised by verbal and non‐verbal communication deficits, impaired social interaction and repetitive, stereotypic behaviours. The aetiology of ASD is most likely a combination… read more here.
Keywords: multiple inbred; inbred strains; prenatal vitamin; vitamin deficiency ... See more keywords
Hybrid Rat Diversity Program (HRDP): A renewable rat resource for systems genetics
Sign Up to like & getrecommendations! Published in 2023 at "Physiology"
DOI: 10.1152/physiol.2023.38.s1.5732554
Abstract: Rats are a major model for studying complex disease mechanisms, behavioral phenotypes, environmental factors, and for drug development and discovery. Inbred rat strains control for genetic background and allow for repeated, reproducible molecular, cellular, and… read more here.
Keywords: hybrid rat; diversity; physiology; inbred strains ... See more keywords
A Natural Occurring Mouse Model with Adgrv1 Mutation of Usher Syndrome 2C and Characterization of its Recombinant Inbred Strains
Sign Up to like & getrecommendations! Published in 2018 at "Cellular Physiology and Biochemistry"
DOI: 10.1159/000491068
Abstract: Background/Aims: Our laboratory discovered a Kunming mouse with enormous electroretinogram (ERG) defects. Its auditory brainstem response (ABR) threshold was significantly elevated and closely resembled the features of Usher syndrome (USH). This study sought to cross… read more here.
Keywords: recombinant inbred; ush mice; usher syndrome; inbred strains ... See more keywords
Single nucleotide polymorphism (SNP) characterisation of mouse inbred strains bred at MRC-National Institute for Medical Research
Sign Up to like & getrecommendations! Published in 2024 at "Laboratory Animals"
DOI: 10.1177/00236772241273070
Abstract: Inbred mouse strains have long proved useful as tools for biomedical research. They remove the effects of genetic background as an experimental variable. Within all mouse colonies, genetic drift is a recognised phenomenon and monitoring… read more here.
Keywords: medical research; inbred strains; institute; strains bred ... See more keywords
Interfrontal Bone Among Inbred Strains of Mice and QTL Mapping
Sign Up to like & getrecommendations! Published in 2019 at "Frontiers in Genetics"
DOI: 10.3389/fgene.2019.00291
Abstract: The interfrontal bone (IF) is a minor skeletal trait residing between the frontal bones. IF is considered a quasi-continuous trait. Genetic and environmental factors appear to play roles in its development. The mechanism(s) underlying IF… read more here.
Keywords: bone among; interfrontal bone; qtl mapping; strains mice ... See more keywords