Articles with "inclusions tdp" as a keyword



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A quantitative biology approach correlates neuronal toxicity with the largest inclusions of TDP-43

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Published in 2022 at "Science Advances"

DOI: 10.1126/sciadv.abm6376

Abstract: A number of neurodegenerative conditions are associated with the formation of cytosolic inclusions of TDP-43 within neurons. We expressed full-length TDP-43 in a motoneuron/neuroblastoma hybrid cell line (NSC-34) and exploited the high-resolution power of stimulated… read more here.

Keywords: quantitative biology; biology approach; inclusions tdp; microscopy ... See more keywords