Incorporation of a Novel CD16-Specific Single-Domain Antibody into Multispecific Natural Killer Cell Engagers With Potent ADCC.
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DOI: 10.1021/acs.molpharmaceut.1c00208
Abstract: Multispecific antibodies that bridge immune effector and tumor cells have shown promising preclinical and clinical efficacies. Here, we isolated and characterized novel llama single-domain antibodies (sdAbs) against CD16. One sdAb, NRC-sdAb048, bound recombinant human and… read more here.
Keywords: incorporation novel; single domain; cd16; anti cd16 ... See more keywords