Synergistic Incorporation of Two ssDNA Activators Enhances the Trans-Cleavage of CRISPR/Cas12a.
Sign Up to like & getrecommendations! Published in 2023 at "Analytical chemistry"
DOI: 10.1021/acs.analchem.3c00414
Abstract: CRISPR/Cas12a has been believed to be powerful in molecular detection and diagnostics due to its amplified trans-cleavage feature. However, the activating specificity and multiple activation mechanisms of the Cas12a system are yet to be elucidated… read more here.
Keywords: incorporation two; trans cleavage; cas12a; ssdna activators ... See more keywords
Metal-free fluoroalkylfluoroalkylselenolation of unactivated alkenes: incorporation of two photoinduced processes
Sign Up to like & getrecommendations! Published in 2020 at "Green Chemistry"
DOI: 10.1039/c9gc03936h
Abstract: The visible-light induced regioselective fluoroalkylfluoroalkylselenolation of unactivated alkenes was realized under metal and oxidant free conditions. The reaction was enabled by incorporation of two distinct photoinduced processes for the generation of two radical coupling partners.… read more here.
Keywords: photoinduced processes; unactivated alkenes; incorporation two; fluoroalkylfluoroalkylselenolation unactivated ... See more keywords