SGLT2 Inhibitors May Increase Creatinine Clearance: Data Mining Utilizing the FDA Adverse Event Report System Database and Pharmacokinetic Study with Rats
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DOI: 10.1159/000546838
Abstract: Abstract Introduction: Augmented renal clearance is a condition in which creatinine clearance exceeds 130 mL/min/1.73 m2. The present study aimed to identify drugs that increase creatinine clearance. Methods: We initially investigated drugs associated with an… read more here.
Keywords: renal clearance; fda adverse; clearance; increase creatinine ... See more keywords
Rapid drop in blood platelet count and increase in creatinine in non-small cell lung cancer (NSCLC) patients treated with osimertinib.
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Clinical Oncology"
DOI: 10.1200/jco.2018.36.15_suppl.e21026
Abstract: e21026Background: Osimertinib has recently become standard of care for advanced, EGFR-mutated NSCLC, and usage in frail populations may incur precautions. Methods: The TREM-study is an investigator... read more here.
Keywords: platelet count; count increase; drop blood; increase creatinine ... See more keywords