Machine-Learning Approach to Increase the Potency and Overcome the Hemolytic Toxicity of Gramicidin S.
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DOI: 10.1021/acs.jmedchem.5c01054
Abstract: Antibiotic resistance is a global health crisis, with multidrug-resistant pathogens like methicillin-resistant Staphylococcus aureus (MRSA) demanding next-generation therapeutics. Tackling this silent pandemic requires innovative strategies beyond traditional drug discovery. We present a machine-learning (ML)-driven computational… read more here.
Keywords: increase potency; potency; machine learning; hemolytic toxicity ... See more keywords