Increased leptin-b expression and metalloprotease expression contributed to the pyridoxine-associated toxicity in zebrafish larvae displaying seizure-like behavior.
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DOI: 10.1016/j.bcp.2020.114294
Abstract: Epilepsy is a common neurological disorder affecting people of all ages, races and ethnic backgrounds world-wide. Vitamin B6 supplementation has been widely used as an adjuvant for treating epilepsy. However, the adverse effects, including nausea… read more here.
Keywords: pyridoxine; associated toxicity; increased leptin; larvae displaying ... See more keywords