Increased miR-21-3p in Injured Brain Microvascular Endothelial Cells after Traumatic Brain Injury Aggravates Blood–Brain Barrier Damage by Promoting Cellular Apoptosis and Inflammation through Targeting MAT2B
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Neurotrauma"
DOI: 10.1089/neu.2018.5728
Abstract: Abstract Our recent articles have reported that increased miR-21-5p in brain after traumatic brain injury (TBI) could improve the neurological outcome through alleviating blood–brain barrier (BBB) ... read more here.
Keywords: brain barrier; increased mir; traumatic brain; brain injury ... See more keywords
Evaluating the Role of Circulating MicroRNAs in Predicting Long-Term Survival Outcomes in Breast Cancer: A Prospective, Multicenter Clinical Trial
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DOI: 10.1097/xcs.0000000000000465
Abstract: BACKGROUND: While long-term outcomes have improved for patients with breast cancer, 20% to 30% will still develop recurrence, and identifying these patients remains a challenge. MicroRNAs (miRNAs) are small, noncoding molecules that modulate genetic expression… read more here.
Keywords: long term; survival; expression; increased mir ... See more keywords
Increased miR‐34c mediates synaptic deficits by targeting synaptotagmin 1 through ROS‐JNK‐p53 pathway in Alzheimer’s Disease
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DOI: 10.1111/acel.13125
Abstract: Alzheimer's disease (AD) and cancer have inverse relationship in many aspects. Some tumor suppressors, including miR‐34c, are decreased in cancer but increased in AD. The upstream regulatory pathways and the downstream mechanisms of miR‐34c in… read more here.
Keywords: ros jnk; jnk p53; increased mir; p53 pathway ... See more keywords