Articles with "increased monoclonal" as a keyword



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Antibody Light Chains: Key to Increased Monoclonal Antibody Yields in Expi293 Cells?

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Published in 2022 at "Antibodies"

DOI: 10.3390/antib11020037

Abstract: When constructing isogenic recombinant IgM–IgG pairs, we discovered that μ heavy chains strongly prefer partnering with λ light chains for optimal IgM expression in transiently cotransfected Expi293 cells. When μ chains were paired with κ… read more here.

Keywords: chains key; light chains; expi293 cells; increased monoclonal ... See more keywords