Preliminary Report: Osteoarthritis and Rheumatoid Arthritis Synovial Fluid Increased Osteoclastogenesis In Vitro by Monocyte Differentiation Pathway Regulating Cytokines
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DOI: 10.1155/2022/2606916
Abstract: Background Rheumatoid arthritis (RA) and osteoarthritis (OA) are common joint diseases associated with changes in local, as well as systemic bone structure and osteoclast function. We investigated how the different soluble inflammatory stimuli in these… read more here.
Keywords: fluid increased; rheumatoid arthritis; increased osteoclastogenesis; fluid ... See more keywords
Increased osteoclastogenesis contributes to bone loss in the Costello syndrome Hras G12V mouse model
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Cell and Developmental Biology"
DOI: 10.3389/fcell.2022.1000575
Abstract: RAS GTPases are ubiquitous GDP/GTP-binding proteins that function as molecular switches in cellular signalling and control numerous signalling pathways and biological processes. Pathogenic mutations in RAS genes severely affect cellular homeostasis, leading to cancer when… read more here.
Keywords: hras g12v; costello syndrome; bone loss; increased osteoclastogenesis ... See more keywords