In Utero Exposure to Mercury Is Associated With Increased Susceptibility to Liver Injury and Inflammation in Childhood
Sign Up to like & getrecommendations! Published in 2021 at "Hepatology"
DOI: 10.1002/hep.31809
Abstract: Nonalcoholic fatty liver disease (NAFLD) is the most prevalent cause of liver disease in children. Mercury (Hg), a ubiquitous toxic metal, has been proposed as an environmental factor contributing to toxicant‐associated fatty liver disease. read more here.
Keywords: mercury associated; increased susceptibility; exposure mercury; associated increased ... See more keywords
Acute kidney injury and aging
Sign Up to like & getrecommendations! Published in 2021 at "Pediatric Nephrology"
DOI: 10.1007/s00467-020-04849-0
Abstract: Our aging population is growing and developing treatments for age-related diseases such as Alzheimer’s and Parkinson’s disease has taken on an increasing urgency and is accompanied by high public awareness. The already high and rising… read more here.
Keywords: kidney injury; aki; acute kidney; increased susceptibility ... See more keywords
Decreased NLRP3 inflammasome expression in aged lung may contribute to increased susceptibility to secondary Streptococcus pneumoniae infection
Sign Up to like & getrecommendations! Published in 2018 at "Experimental Gerontology"
DOI: 10.1016/j.exger.2017.11.010
Abstract: &NA; Post‐viral pneumococcal pneumonia is a leading morbidity and mortality in older patients (≥65 years of age). The goal of our current study is to understand the impact of chronological aging on innate immune responses… read more here.
Keywords: infection; pneumoniae infection; expression; nlrp3 inflammasome ... See more keywords
Galangin Prevents Increased Susceptibility to Pentylenetetrazol-Stimulated Seizures by Prostaglandin E2
Sign Up to like & getrecommendations! Published in 2019 at "Neuroscience"
DOI: 10.1016/j.neuroscience.2019.06.002
Abstract: Epilepsy is one of the most common chronic neurological diseases. It is characterized by recurrent epileptic seizures, where one-third of patients are refractory to existing treatments. Evidence revealed the association between neuroinflammation and increased susceptibility… read more here.
Keywords: susceptibility pentylenetetrazol; susceptibility; pge2; ptz ... See more keywords
Impaired calcineurin signaling in myeloid cells results in downregulation of pentraxin-3 and increased susceptibility to aspergillosis
Sign Up to like & getrecommendations! Published in 2017 at "Mucosal Immunology"
DOI: 10.1038/mi.2016.52
Abstract: Treatment of post-transplant patients with immunosuppressive drugs targeting the calcineurin–nuclear factor of activated T cells (NFAT) pathway, including cyclosporine A or tacrolimus, is commonly associated with a higher incidence of opportunistic infections, such as Aspergillus… read more here.
Keywords: calcineurin signaling; susceptibility; calcineurin; myeloid cells ... See more keywords
Increased Susceptibility to Plasmodium falciparum in Infants is associated with Low, not High, Placental Malaria Parasitemia
Sign Up to like & getrecommendations! Published in 2017 at "Scientific Reports"
DOI: 10.1038/s41598-017-18574-6
Abstract: Risk of malaria in infants can be influenced by prenatal factors. In this study, the potential for placental parasitemia at delivery in predicting susceptibility of infants to Plasmodium falciparum (Pf) infections was evaluated. Seventy-two newborns… read more here.
Keywords: placental parasitemia; susceptibility; placental malaria; plasmodium falciparum ... See more keywords
Increased susceptibility to cortical spreading depression and epileptiform activity in a mouse model for FHM2
Sign Up to like & getrecommendations! Published in 2018 at "Scientific Reports"
DOI: 10.1038/s41598-018-35285-8
Abstract: Migraine is a highly prevalent, debilitating, episodic headache disorder affecting roughly 15% of the population. Familial hemiplegic migraine type 2 (FHM2) is a rare subtype of migraine caused by mutations in the ATP1A2 gene, encoding… read more here.
Keywords: fhm2; increased susceptibility; epileptiform activity; mouse model ... See more keywords
Mutations of folC cause increased susceptibility to sulfamethoxazole in Mycobacterium tuberculosis
Sign Up to like & getrecommendations! Published in 2021 at "Scientific Reports"
DOI: 10.1038/s41598-020-80213-4
Abstract: Previous studies showed that mutation of folC caused decreased expression of the dihydropteroate synthase encoding gene folP2 in Mycobacterium tuberculosis (M. tuberculosis). We speculated that mutation of folC in M. tuberculosis might affect the susceptibility… read more here.
Keywords: susceptibility; folc mutants; susceptibility sulfamethoxazole; tuberculosis ... See more keywords
Increased Susceptibility of Cattle to Intranasal RVFV Infection
Sign Up to like & getrecommendations! Published in 2020 at "Frontiers in Veterinary Science"
DOI: 10.3389/fvets.2020.00137
Abstract: Rift Valley Fever virus (RVFV) is a zoonotic mosquito-borne virus that belongs to the Phenuiviridae family. Infections in animal herds cause abortion storms, high mortality rates in neonates, and mild to severe symptoms. Infected animals… read more here.
Keywords: cattle intranasal; infection; intranasal rvfv; increased susceptibility ... See more keywords
Increased susceptibility of aging gastric mucosa to injury and delayed healing: Clinical implications
Sign Up to like & getrecommendations! Published in 2018 at "World Journal of Gastroenterology"
DOI: 10.3748/wjg.v24.i42.4721
Abstract: In this editorial we comment on the article by Fukushi K et al published in the recent issue of the World Journal of Gastroenterology 2018; 24(34): 3908-3918. We focus specifically on the mechanisms of the… read more here.
Keywords: gastric mucosa; gastroenterology; aging gastric; increased susceptibility ... See more keywords