Increased the TMZ concentration in brain by poly(2-ethyl-2-oxazoline) conjugated temozolomide prodrug micelles for glioblastoma treatment
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DOI: 10.1016/j.eurpolymj.2020.110232
Abstract: Abstract The current treatment of glioblastoma (GBM) remains challenging. Temozolomide (TMZ), a first-line chemotherapy drug used to treat glioblastoma, is rapidly cleared under normal physiological conditions and has poor stability, which severely limits its efficacy.… read more here.
Keywords: increased tmz; ethyl oxazoline; treatment; tmz ... See more keywords