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ErbB4 signaling in dopaminergic axonal projections increases extracellular dopamine levels and regulates spatial/working memory behaviors

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Published in 2018 at "Molecular Psychiatry"

DOI: 10.1038/mp.2017.132

Abstract: Genetic variants of Neuregulin 1 (NRG1) and its neuronal tyrosine kinase receptor ErbB4 are associated with risk for schizophrenia, a neurodevelopmental disorder characterized by excitatory/inhibitory imbalance and dopamine (DA) dysfunction. To date, most ErbB4 studies… read more here.

Keywords: erbb4; signaling dopaminergic; erbb4 signaling; spatial working ... See more keywords