Rapamycin increases oxidative metabolism and enhances metabolic flexibility in human cardiac fibroblasts
Sign Up to like & getrecommendations! Published in 2018 at "GeroScience"
DOI: 10.1007/s11357-018-0030-2
Abstract: Inhibition of mTOR signaling using rapamycin has been shown to increase lifespan and healthspan in multiple model organisms; however, the precise mechanisms for the beneficial effects of rapamycin remain uncertain. We have previously reported that… read more here.
Keywords: rapamycin increases; oxidative metabolism; senescence; increases oxidative ... See more keywords
The uremic toxin methylguanidine increases the oxidative metabolism and accelerates the apoptosis of canine neutrophils.
Sign Up to like & getrecommendations! Published in 2017 at "Veterinary immunology and immunopathology"
DOI: 10.1016/j.vetimm.2017.01.006
Abstract: We investigated the hypothesis that the increased concentration of plasma methylguanidine (MG) increases oxidative metabolism and accelerates apoptosis of neutrophils from dogs with chronic kidney disease (CKD). To achieve this, the levels of MG were… read more here.
Keywords: oxidative metabolism; metabolism; metabolism accelerates; increases oxidative ... See more keywords