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   Articles with "incretin effect" as a keyword



Loss of incretin effect contributes to postprandial hyperglycaemia in cystic fibrosis‐related diabetes

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recommendations! Published in 2019 at "Diabetic Medicine"

DOI: 10.1111/dme.14121

Abstract: To investigate the incretin axis in people with cystic fibrosis. read more here.

Keywords: effect contributes; cystic fibrosis; incretin effect; loss incretin ... See more keywords

Anti‐incretin effect: The other face of Janus in human glucose homeostasis

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recommendations! Published in 2019 at "Obesity Reviews"

DOI: 10.1111/obr.12917

Abstract: The provocative idea that type 2 diabetes (T2D) may be a surgically treated disorder is based on accumulating evidence suggesting impressive remission rates of obesity and diabetes following bariatric surgery interventions. According to the “anti‐incretin”… read more here.

Keywords: janus human; incretin effect; effect face; anti incretin ... See more keywords

The Glucagon Receptor Antagonist LY2409021 does not affect gastrointestinal-mediated glucose disposal or the incretin effect in individuals with and without type 2 diabetes.

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recommendations! Published in 2022 at "European journal of endocrinology"

DOI: 10.1530/eje-22-0291

Abstract: OBJECTIVE Gastrointestinal-mediated glucose disposal (GIGD) during oral glucose tolerance test (OGTT) reflects the percentage of glucose disposal caused by mechanisms elicited by the oral route of glucose administration. GIGD is reduced in patients with type… read more here.

Keywords: glucose; incretin effect; effect; glucagon receptor ... See more keywords
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61-OR: Genetic and Metabolic Determinants of the Incretin Effect in Obese Adolescent with Prediabetes

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recommendations! Published in 2020 at "Diabetes"

DOI: 10.2337/db20-61-or

Abstract: Prediabetes and type 2 diabetes in obese youths are associated with a reduced incretin effect. Herein, we investigated the metabolic and genetic determinants of incretin effect in obese youths with normal and impaired glucose tolerance.… read more here.

Keywords: insulin; determinants incretin; incretin effect; effect obese ... See more keywords

18-OR: Lower Incretin Effect and Reduced GIP Characterize the Metabolic Phenotype of People with Multiple Islet Autoantibodies and Normal Glucose Tolerance

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recommendations! Published in 2025 at "Diabetes"

DOI: 10.2337/db25-18-or

Abstract: Introduction and Objective: The incretin effect measures the contribution of gut-derived hormones GLP-1 and GIP to insulin secretion. There is limited evidence of the role of incretins in preclinical type 1 diabetes (T1D). We compared… read more here.

Keywords: incretin effect; none; stage; glucose tolerance ... See more keywords

The integrated incretin effect is reduced by both glucose intolerance and obesity in Japanese subjects

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recommendations! Published in 2024 at "Frontiers in Endocrinology"

DOI: 10.3389/fendo.2024.1301352

Abstract: Introduction Incretin-based drugs are extensively utilized in the treatment of type 2 diabetes (T2D), with remarkable clinical efficacy. These drugs were developed based on findings that the incretin effect is reduced in T2D. The incretin… read more here.

Keywords: incretin effect; effect; effect reduced; glucose tolerance ... See more keywords