Synthesis and characterization of 2-benzylidene-1,3-indandione derivatives as in vitro quantification of amyloid fibrils
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DOI: 10.1007/s13738-019-01776-2
Abstract: Timely detection of amyloid aggregations has a critical role in the treatment of degenerative nervous system disorders such as Alzheimer’s, Parkinson’s disease and systemic amyloidosis. Thioflavin T (ThT) is a dye considered for the detection… read more here.
Keywords: amyloid; benzylidene indandione; indandione derivatives; amyloid fibrils ... See more keywords
2-Arylidene-1-indandiones as Pleiotropic Agents with Antioxidant and Inhibitory Enzymes Activities †
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DOI: 10.3390/molecules24234411
Abstract: Indandiones are a relatively new group of compounds presenting a wide range of biological activities. The synthesis of these compounds was performed via a Knoevenagel reaction between an aldehyde and 1,3-indandione and were obtained with… read more here.
Keywords: indandione showed; arylidene indandiones; indandiones pleiotropic; arylidene indandione ... See more keywords