Indel detection from RNA-seq data: tool evaluation and strategies for accurate detection of actionable mutations
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DOI: 10.1093/bib/bbw069
Abstract: Abstract Driver somatic mutations are a hallmark of a tumor that can be used for diagnosis and targeted therapy. Mutations are primarily detected from tumor DNA. As dynamic molecules of gene activities, transcriptome profiling by… read more here.
Keywords: strategies accurate; rna seq; detection; indel detection ... See more keywords
A Comprehensive Review of Indel Detection Methods for Identification of Zebrafish Knockout Mutants Generated by Genome-Editing Nucleases
Sign Up to like & getrecommendations! Published in 2022 at "Genes"
DOI: 10.3390/genes13050857
Abstract: The use of zebrafish in functional genomics and disease modeling has become popular due to the ease of targeted mutagenesis with genome editing nucleases, i.e., zinc finger nucleases (ZFNs), transcription activator-like effector nucleases (TALENs), and… read more here.
Keywords: genome editing; comprehensive review; indel detection; knockout mutants ... See more keywords