Frameshift indels introduced by genome editing can lead to in-frame exon skipping
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DOI: 10.1371/journal.pone.0178700
Abstract: The introduction of frameshift indels by genome editing has emerged as a powerful technique to study the functions of uncharacterized genes in cell lines and model organisms. Such mutations should lead to mRNA degradation owing… read more here.
Keywords: genome editing; indels introduced; frameshift indels; exon skipping ... See more keywords