FIT, a regulatory hub for iron deficiency and stress signaling in roots, and FIT-dependent and -independent gene signatures
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Experimental Botany"
DOI: 10.1093/jxb/eraa012
Abstract: Abstract Iron (Fe) is vital for plant growth. Plants balance the beneficial and toxic effects of this micronutrient, and tightly control Fe uptake and allocation. Here, we review the role of the basic helix–loop–helix (bHLH)… read more here.
Keywords: independent gene; regulatory hub; fit dependent; gene signatures ... See more keywords
On the independent gene trees assumption in phylogenomic studies
Sign Up to like & getrecommendations! Published in 2017 at "Molecular Ecology"
DOI: 10.1111/mec.14274
Abstract: Multilocus coalescent methods for inferring species trees or historical demographic parameters typically require the assumption that gene trees for sampled SNPs or DNA sequence loci are conditionally independent given their species tree. In practice, researchers… read more here.
Keywords: independent gene; criterion; phylogenomic studies; ecology ... See more keywords
Tyrosine Kinase Inhibitor Independent Gene Expression Signature in CML Offers New Targets for LSPC Eradication Therapy
Sign Up to like & getrecommendations! Published in 2022 at "Cancers"
DOI: 10.3390/cancers14215253
Abstract: Tyrosine kinase inhibitors (TKI) have revolutionised the treatment of CML. However, TKI do not eliminate the leukaemia stem cells (LSC), which can reinitiate the disease. Thus, finding new therapeutic targets in CML LSC is key… read more here.
Keywords: gemtuzumab ozogamicin; cml; tyrosine kinase; gene expression ... See more keywords