The chemopreventive isothiocyanate sulforaphane reduces anoikis resistance and anchorage‐independent growth in non‐small cell human lung cancer cells
Sign Up to like & getrecommendations! Published in 2019 at "Toxicology and Applied Pharmacology"
DOI: 10.1016/j.taap.2018.10.020
Abstract: ABSTRACT The capacity of cancer cells to resist detachment‐induced apoptosis, i.e. anoikis, as well as anchorage‐independent growth are crucial prerequisites for tumor metastasis. Therefore, agents interfering these properties may provide novel anti‐metastatic strategies. Sulforaphane (SFN),… read more here.
Keywords: anchorage independent; sfn; independent growth; cancer cells ... See more keywords
MiR-193b, downregulated in Ewing Sarcoma, targets the ErbB4 oncogene to inhibit anchorage-independent growth
Sign Up to like & getrecommendations! Published in 2017 at "PLoS ONE"
DOI: 10.1371/journal.pone.0178028
Abstract: Ewing Sarcoma is an aggressive, oncofusion-driven, malignant neoplasm of bone and soft tissue affecting predominantly children and young adults. Seeking to identify potential novel therapeutic targets/agents for this disease, our previous studies uncovered microRNAs regulated… read more here.
Keywords: anchorage independent; independent growth; ewing sarcoma; mir 193b ... See more keywords