Monitoring of Atg5-Independent Mitophagy.
Sign Up to like & getrecommendations! Published in 2018 at "Methods in molecular biology"
DOI: 10.1007/7651_2017_16
Abstract: Mitophagy is a mitochondrial quality control mechanism where damaged and surplus mitochondria are removed by autophagy. There are at least two different mammalian autophagy pathways: the Atg5-dependent conventional pathway and an Atg5-independent alternative pathway; the… read more here.
Keywords: independent mitophagy; biology; monitoring atg5; atg5 independent ... See more keywords
GAK and PRKCD are positive regulators of PRKN-independent mitophagy
Sign Up to like & getrecommendations! Published in 2021 at "Nature Communications"
DOI: 10.1038/s41467-021-26331-7
Abstract: The mechanisms involved in programmed or damage-induced removal of mitochondria by mitophagy remains elusive. Here, we have screened for regulators of PRKN-independent mitophagy using an siRNA library targeting 197 proteins containing lipid interacting domains. We… read more here.
Keywords: mitophagy; independent mitophagy; prkn independent; gak prkcd ... See more keywords
Regulation of PRKN-Independent Mitophagy.
Sign Up to like & getrecommendations! Published in 2021 at "Autophagy"
DOI: 10.1080/15548627.2021.1888244
Abstract: Mitochondria are dynamic, multifunctional cellular organelles that play a fundamental role in maintaining cellular homeostasis. Keeping the quality of mitochondria in check is of essential importance for functioning and survival of the cells. Selective autophagic… read more here.
Keywords: regulation prkn; independent mitophagy; prkn independent; prkn ... See more keywords