Electrostatically driven complex coacervation and amyloid aggregation of tau are independent processes with overlapping conditions.
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DOI: 10.1021/acschemneuro.9b00627
Abstract: Amyloid aggregation of the microtubule binding protein tau is a hallmark of many neurodegenerative diseases. Recently, tau has been found to undergo liquid-liquid phase separation (LLPS) by an electrostatically driven complex coacervation (CC) mechanism near… read more here.
Keywords: aggregation; tau; aggregation tau; electrostatically driven ... See more keywords