Articles with "independent pxr" as a keyword



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CYP3A suppression during diet-induced nonalcoholic fatty liver disease is independent of PXR regulation.

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Published in 2019 at "Chemico-biological interactions"

DOI: 10.1016/j.cbi.2019.05.038

Abstract: Cytochrome P450 3A (CYP3A) activity is inhibited, and its expression is suppressed during many diseases, including nonalcoholic fatty liver disease (NAFLD). However, the mechanism is controversial. Here, we report that PXR may not take part… read more here.

Keywords: fatty liver; cyp3a; pxr; nonalcoholic fatty ... See more keywords