The K+-Dependent and -Independent Pyruvate Kinases Acquire the Active Conformation by Different Mechanisms
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DOI: 10.3390/ijms23031347
Abstract: Eukarya pyruvate kinases possess glutamate at position 117 (numbering of rabbit muscle enzyme), whereas bacteria have either glutamate or lysine. Those with E117 are K+-dependent, whereas those with K117 are K+-independent. In a phylogenetic tree,… read more here.
Keywords: pyruvate kinases; dependent independent; independent pyruvate; active conformation ... See more keywords