Ubiquitin-Dependent and -Independent Roles of E3 Ligase RIPLET in Innate Immunity
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DOI: 10.1016/j.cell.2019.03.017
Abstract: The conventional view posits that E3 ligases function primarily through conjugating ubiquitin (Ub) to their substrate molecules. We report here that RIPLET, an essential E3 ligase in antiviral immunity, promotes the antiviral signaling activity of… read more here.
Keywords: immunity; rig; dependent independent; ubiquitin dependent ... See more keywords
Chromophore-Independent Roles of Opsin Apoproteins in Drosophila Mechanoreceptors
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DOI: 10.1016/j.cub.2019.07.036
Abstract: Rhodopsins, the major light-detecting molecules of animal visual systems [1], consist of opsin apoproteins that covalently bind a retinal chromophore with a conserved lysine residue [1, 2]. In addition to capturing photons, this chromophore contributes… read more here.
Keywords: chromophore; chromophore independent; independent roles; function ... See more keywords