Adrenergic-Independent Signaling via CHRNA2 Regulates Beige Fat Activation.
Sign Up to like & getrecommendations! Published in 2020 at "Developmental cell"
DOI: 10.1016/j.devcel.2020.05.017
Abstract: Maintaining energy homeostasis upon environmental challenges, such as cold or excess calorie intake, is essential to the fitness and survival of mammals. Drug discovery efforts targeting β-adrenergic signaling have not been fruitful after decades of… read more here.
Keywords: chrna2; beige fat; independent signaling; via chrna2 ... See more keywords
Lipopolysaccharide-induced DC-SIGN/TLR4 crosstalk activates NLRP3 inflammasomes via MyD88-independent signaling in gastric epithelial cells.
Sign Up to like & getrecommendations! Published in 2020 at "Experimental cell research"
DOI: 10.1016/j.yexcr.2020.112292
Abstract: Abnormal pattern recognition receptor (PRR) signaling plays an important role in gastric mucosal damage caused by stomach microbiota; however, the underlying molecular mechanisms remain obscure. Here, we show that DC-SIGN, a surface phenotype marker of… read more here.
Keywords: gastric epithelial; epithelial cells; myd88 independent; induced sign ... See more keywords
Uroguanylin increases Ca2+ concentration in astrocytes via guanylate cyclase C-independent signaling pathway.
Sign Up to like & getrecommendations! Published in 2021 at "Croatian medical journal"
DOI: 10.21203/rs.3.rs-52912/v1
Abstract: AIM To investigate the cyclic guanosine monophosphate (cGMP)/guanylate cyclase C (GC-C)-independent signaling pathway in astrocytes, which are a suitable model due to their lack of GC-C expression. METHODS Patch clamp was performed and intracellular Ca2+… read more here.
Keywords: ca2 concentration; concentration astrocytes; guanylate cyclase; independent signaling ... See more keywords