Nicotinamide, a vitamin B3 ameliorates depressive behaviors independent of SIRT1 activity in mice
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DOI: 10.1186/s13041-020-00703-4
Abstract: Sirtuin 1 (SIRT1), is a nicotinamide adenine dinucleotide (NAD + )-dependent protein deacetylase and a candidate gene for depression. Nicotinamide (NAM), a form of vitamin B3, is reported as a potential inhibitor of SIRT1. Our… read more here.
Keywords: independent sirt1; depression; depressive behaviors; sirt1 activity ... See more keywords