Articles with "independently gasdermin" as a keyword



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Early endosome autoantigen 1 regulates IL-1β release upon caspase-1 activation independently of gasdermin D membrane permeabilization

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Published in 2019 at "Scientific Reports"

DOI: 10.1038/s41598-019-42298-4

Abstract: Unconventional protein secretion represents an important process of the inflammatory response. The release of the pro-inflammatory cytokine interleukin (IL)-1β which burst during pyroptosis as a consequence of gasdermin D plasma membrane pore formation, can also… read more here.

Keywords: caspase; caspase activation; early endosome; endosome autoantigen ... See more keywords