Ancillary molecular testing of indeterminate thyroid nodules
Sign Up to like & getrecommendations! Published in 2018 at "Cancer Cytopathology"
DOI: 10.1002/cncy.22012
Abstract: Cytological specimens from thyroid nodules are increasingly being adopted as the first available material for cost effectively managing patients in the era of personalized medicine. Cytology aspirates not only play a central role in providing… read more here.
Keywords: thyroid nodules; indeterminate thyroid; molecular testing; ancillary molecular ... See more keywords
Risk stratification of cytologically indeterminate thyroid nodules with nondiagnostic or benign cytology on repeat FNA: Implications for molecular testing and surveillance
Sign Up to like & getrecommendations! Published in 2023 at "Cancer Cytopathology"
DOI: 10.1002/cncy.22684
Abstract: Evidence guiding the management of cytologically indeterminate thyroid nodules with nondiagnostic (ND) or benign cytology on repeat fine‐needle aspiration (FNA) is limited. This study evaluates the utility of molecular testing and estimates the risk of… read more here.
Keywords: thyroid nodules; cytologically indeterminate; thyroid; nodules nondiagnostic ... See more keywords
Determining the molecular test for indeterminate thyroid nodules best suited for our practice: A quality assurance study
Sign Up to like & getrecommendations! Published in 2019 at "Diagnostic Cytopathology"
DOI: 10.1002/dc.24091
Abstract: Currently, molecular studies are widely used as a guiding tool in further management of cytologically indeterminate thyroid nodules. At our institution, clinicians have recently expressed concern over receiving “less positive molecular results” upon switching from… read more here.
Keywords: thyroid nodules; determining molecular; test indeterminate; indeterminate thyroid ... See more keywords
Indeterminate thyroid nodules in the era of molecular genomics
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DOI: 10.1002/mgg3.1288
Abstract: Indeterminate thyroid nodules are diagnosed in up to 30% of fine‐needle aspirations and the risk of malignancy in these cases are highly variable. Consequently, managing these nodules has been a challenge. While a diagnostic thyroidectomy… read more here.
Keywords: thyroid nodules; indeterminate thyroid; molecular genomics; era molecular ... See more keywords
Radiomics analysis improves 18FDG PET/CT-based risk stratification of cytologically indeterminate thyroid nodules
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DOI: 10.1007/s12020-021-02856-1
Abstract: As ~25% of cytologically indeterminate thyroid nodules harbour malignancy, diagnostic lobectomy is still performed in many cases. 18FDG PET/CT rules out malignancy in visually negative nodules; however, none of the currently available interpretation criteria differentiates… read more here.
Keywords: thyroid nodules; pet; indeterminate thyroid; cytologically indeterminate ... See more keywords
Indeterminate Thyroid Nodules and Advances in Molecular Pathology.
Sign Up to like & getrecommendations! Published in 2023 at "Seminars in diagnostic pathology"
DOI: 10.1053/j.semdp.2023.05.001
Abstract: Thyroid cytology has in recent years been augmented by molecular testing for indeterminate lesions. Three commercial molecular tests are available which provide variable amounts of detail regarding the genetic alterations identified in a sample. This… read more here.
Keywords: pathology indeterminate; thyroid nodules; thyroid; pathology ... See more keywords
A machine-learning algorithm for distinguishing malignant from benign indeterminate thyroid nodules using ultrasound radiomic features
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Medical Imaging"
DOI: 10.1117/1.jmi.9.3.034501
Abstract: Abstract. Background: Ultrasound (US)-guided fine needle aspiration (FNA) cytology is the gold standard for the evaluation of thyroid nodules. However, up to 30% of FNA results are indeterminate, requiring further testing. In this study, we… read more here.
Keywords: thyroid nodules; thyroid; machine learning; pathology ... See more keywords
Clinical and ultrasonographic features in cancer risk stratification of indeterminate thyroid nodules
Sign Up to like & getrecommendations! Published in 2022 at "Saudi Medical Journal"
DOI: 10.15537/smj.2022.43.5.20220045
Abstract: Objectives: To estimate the risk of malignancy in indeterminate thyroid nodules and to determine whether certain clinical or radiological parameters can predict the risk of malignancy. Methods: This retrospective study enrolled all adult patients (age… read more here.
Keywords: thyroid nodules; malignancy; indeterminate thyroid; risk ... See more keywords
Approach to cytological indeterminate thyroid nodules.
Sign Up to like & getrecommendations! Published in 2019 at "Gland surgery"
DOI: 10.21037/gs.2018.12.06
Abstract: The indeterminate thyroid nodules diagnosed by fine-needle aspiration cytology (FNAC)represents a problem for both cytopathologists and clinicians. The former sometimes use this diagnostic category as a sort of basket, putting in cases that they do… read more here.
Keywords: thyroid; approach cytological; indeterminate thyroid; thyroid nodules ... See more keywords
Surgical management of cytologically indeterminate thyroid nodules.
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DOI: 10.21037/gs.2019.01.03
Abstract: Nodules in the thyroid are frequent. Preoperative investigations including fine-needle cytology and ultrasound cannot in all patients rule out malignancy. Thus, surgical excision for histopathologic examination is often needed. In this narrative review, we examine… read more here.
Keywords: cytology; thyroid; surgical management; indeterminate thyroid ... See more keywords
Diagnostic Performance of Afirma and Interpace Diagnostics Genetic Testing in Indeterminate Thyroid Nodules: A Single Center Study
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DOI: 10.3390/cancers15072098
Abstract: Simple Summary Molecular testing can stratify the risk of malignancy among indeterminate thyroid nodules and subsequently reduce the need for diagnostic surgery. We assessed the performance of the GSC + XA; ThyGeNEXT + ThyraMIR, and… read more here.
Keywords: thyroid nodules; gsc; genetic testing; thygenext thyramir ... See more keywords