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   Articles with "indeterminate thyroid" as a keyword



Ancillary molecular testing of indeterminate thyroid nodules

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recommendations! Published in 2018 at "Cancer Cytopathology"

DOI: 10.1002/cncy.22012

Abstract: Cytological specimens from thyroid nodules are increasingly being adopted as the first available material for cost effectively managing patients in the era of personalized medicine. Cytology aspirates not only play a central role in providing… read more here.

Keywords: thyroid nodules; indeterminate thyroid; molecular testing; ancillary molecular ... See more keywords

Risk stratification of cytologically indeterminate thyroid nodules with nondiagnostic or benign cytology on repeat FNA: Implications for molecular testing and surveillance

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recommendations! Published in 2023 at "Cancer Cytopathology"

DOI: 10.1002/cncy.22684

Abstract: Evidence guiding the management of cytologically indeterminate thyroid nodules with nondiagnostic (ND) or benign cytology on repeat fine‐needle aspiration (FNA) is limited. This study evaluates the utility of molecular testing and estimates the risk of… read more here.

Keywords: thyroid nodules; cytologically indeterminate; thyroid; nodules nondiagnostic ... See more keywords

Determining the molecular test for indeterminate thyroid nodules best suited for our practice: A quality assurance study

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recommendations! Published in 2019 at "Diagnostic Cytopathology"

DOI: 10.1002/dc.24091

Abstract: Currently, molecular studies are widely used as a guiding tool in further management of cytologically indeterminate thyroid nodules. At our institution, clinicians have recently expressed concern over receiving “less positive molecular results” upon switching from… read more here.

Keywords: thyroid nodules; determining molecular; test indeterminate; indeterminate thyroid ... See more keywords

ThyroSeq overview on indeterminate thyroid nodules: An institutional experience

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recommendations! Published in 2024 at "Diagnostic Cytopathology"

DOI: 10.1002/dc.25311

Abstract: Molecular triage of indeterminate thyroid aspirates offers the opportunity to stratify the risk of malignancy (ROM) more accurately. Here we examine our experience with ThyroSeq v3 testing. read more here.

Keywords: indeterminate thyroid; thyroseq overview; experience thyroseq; experience ... See more keywords
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Indeterminate thyroid nodules in the era of molecular genomics

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recommendations! Published in 2020 at "Molecular Genetics & Genomic Medicine"

DOI: 10.1002/mgg3.1288

Abstract: Indeterminate thyroid nodules are diagnosed in up to 30% of fine‐needle aspirations and the risk of malignancy in these cases are highly variable. Consequently, managing these nodules has been a challenge. While a diagnostic thyroidectomy… read more here.

Keywords: thyroid nodules; indeterminate thyroid; molecular genomics; era molecular ... See more keywords
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Radiomics analysis improves 18FDG PET/CT-based risk stratification of cytologically indeterminate thyroid nodules

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recommendations! Published in 2021 at "Endocrine"

DOI: 10.1007/s12020-021-02856-1

Abstract: As ~25% of cytologically indeterminate thyroid nodules harbour malignancy, diagnostic lobectomy is still performed in many cases. 18FDG PET/CT rules out malignancy in visually negative nodules; however, none of the currently available interpretation criteria differentiates… read more here.

Keywords: thyroid nodules; pet; indeterminate thyroid; cytologically indeterminate ... See more keywords

Biomarker identification through spatial proteomics for the characterization of indeterminate thyroid nodules

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recommendations! Published in 2025 at "Endocrine"

DOI: 10.1007/s12020-025-04383-9

Abstract: The identification of novel molecular biomarkers may assist in the characterization of indeterminate thyroid nodules, which pose significant diagnostic challenges. Here, we aimed to explore the potential of proteomic analyses to support biomarker discovery in… read more here.

Keywords: indeterminate thyroid; thyroid nodules; identification; thyroid ... See more keywords
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Indeterminate Thyroid Nodules and Advances in Molecular Pathology.

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recommendations! Published in 2023 at "Seminars in diagnostic pathology"

DOI: 10.1053/j.semdp.2023.05.001

Abstract: Thyroid cytology has in recent years been augmented by molecular testing for indeterminate lesions. Three commercial molecular tests are available which provide variable amounts of detail regarding the genetic alterations identified in a sample. This… read more here.

Keywords: pathology indeterminate; thyroid nodules; thyroid; pathology ... See more keywords

Molecular Profiling and Surgical Outcomes in Indeterminate Thyroid Nodules: Experience from a Tertiary Care Center

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recommendations! Published in 2024 at "American Journal of Clinical Pathology"

DOI: 10.1093/ajcp/aqae129.279

Abstract: This study examines molecular results(MR) and surgical follow-up(SFU) of cytologically- indeterminate thyroid nodules. Atypia-of-undetermined significance/suspicious-for-follicular-neoplasm cases that underwent Quest/ThyroSeq molecular testing between 2015-2022 were analyzed for MR, SFU and lymph node metastasis(LNM). 417 cases(Quest=192, ThyroSeq=225).… read more here.

Keywords: braf; ptc; indeterminate thyroid; thyroid nodules ... See more keywords

A machine-learning algorithm for distinguishing malignant from benign indeterminate thyroid nodules using ultrasound radiomic features

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recommendations! Published in 2022 at "Journal of Medical Imaging"

DOI: 10.1117/1.jmi.9.3.034501

Abstract: Abstract. Background: Ultrasound (US)-guided fine needle aspiration (FNA) cytology is the gold standard for the evaluation of thyroid nodules. However, up to 30% of FNA results are indeterminate, requiring further testing. In this study, we… read more here.

Keywords: thyroid nodules; thyroid; machine learning; pathology ... See more keywords

Clinical and ultrasonographic features in cancer risk stratification of indeterminate thyroid nodules

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recommendations! Published in 2022 at "Saudi Medical Journal"

DOI: 10.15537/smj.2022.43.5.20220045

Abstract: Objectives: To estimate the risk of malignancy in indeterminate thyroid nodules and to determine whether certain clinical or radiological parameters can predict the risk of malignancy. Methods: This retrospective study enrolled all adult patients (age… read more here.

Keywords: thyroid nodules; malignancy; indeterminate thyroid; risk ... See more keywords