Reevaluate In Vitro CYP3A Index Reactions of Benzodiazepines and Steroids between Humans and Dogs
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DOI: 10.1124/dmd.122.000864
Abstract: Cytochrome P450 3A (CYP3A), the most important class of drug-metabolizing enzymes, participates in the metabolism of half of clinically used drugs. The CYP3A index reactions of dogs, one of the most widely used preclinical nonrodent… read more here.
Keywords: humans dogs; cyp3a index; index reactions; hydroxylation ... See more keywords