Abstract 4652: Targeted nanomedicines improve therapeutic indices of RAF and MEK inhibitors
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DOI: 10.1158/1538-7445.am2018-4652
Abstract: Potent kinase inhibitors have been developed to treat tumors, but they suppress signaling in normal cells so that their dosing and ability to inhibit the pathway are limited by toxicity, resulting in a narrow therapeutic… read more here.
Keywords: indices raf; therapeutic indices; targeted nanomedicines; improve therapeutic ... See more keywords