Evergreened drugs or evergreened profits?
Sign Up to like & getrecommendations! Published in 2022 at "Journal of evaluation in clinical practice"
DOI: 10.1111/jep.13695
Abstract: BACKGROUND Branded drugs contribute disproportionately to high prescription drug spending. Pharmaceutical companies utilize patent extension "evergreening" techniques that contribute to high drug costs. AIMS This article describes various patent extension techniques and analyzes the tactic… read more here.
Keywords: patent extension; individual constituents; fixed dose; dose combinations ... See more keywords
Whole-Genome Sequencing and Genetic Analysis Reveal Novel Stress Responses to Individual Constituents of Essential Oils in Escherichia coli
Sign Up to like & getrecommendations! Published in 2018 at "Applied and Environmental Microbiology"
DOI: 10.1128/aem.02538-17
Abstract: ABSTRACT Food preservation by the use of essential oils (EOs) is being extensively studied because of the antimicrobial properties of their individual constituents (ICs). Three resistant mutants (termed CAR, CIT, and LIM) of Escherichia coli… read more here.
Keywords: whole genome; escherichia coli; resistance; genome sequencing ... See more keywords