Multiple mutations within individual oncogenes
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DOI: 10.1111/cas.14699
Abstract: Recent studies of the cancer genome have identified numerous patients harboring multiple mutations (MM) within individual oncogenes. These MM (de novo MM) in cis synergistically activate the mutated oncogene and promote tumorigenesis, indicating a positive… read more here.
Keywords: mutations within; evolution; multiple mutations; cancer ... See more keywords