Predictors of outcomes after surgery for medically intractable insular epilepsy: A systematic review and individual participant data meta‐analysis
Sign Up to like & getrecommendations! Published in 2022 at "Epilepsia Open"
DOI: 10.1002/epi4.12663
Abstract: Insular epilepsy (IE) is an increasingly recognized cause of drug‐resistant epilepsy amenable to surgery. However, concerns of suboptimal seizure control and permanent neurological morbidity hamper widespread adoption of surgery for IE. We performed a systematic… read more here.
Keywords: surgery; individual participant; insular epilepsy; systematic review ... See more keywords
Evaluation of biomarkers for treatment selection using individual participant data from multiple clinical trials.
Sign Up to like & getrecommendations! Published in 2018 at "Statistics in medicine"
DOI: 10.1002/sim.7608
Abstract: Biomarkers that predict treatment effects may be used to guide treatment decisions, thus improving patient outcomes. A meta-analysis of individual participant data (IPD) is potentially more powerful than a single-study data analysis in evaluating markers… read more here.
Keywords: treatment selection; treatment; clinical trials; participant data ... See more keywords
A Bayesian hierarchical model for individual participant data meta-analysis of demand curves.
Sign Up to like & getrecommendations! Published in 2022 at "Statistics in medicine"
DOI: 10.1002/sim.9354
Abstract: Individual participant data meta-analysis is a frequently used method to combine and contrast data from multiple independent studies. Bayesian hierarchical models are increasingly used to appropriately take into account potential heterogeneity between studies. In this… read more here.
Keywords: analysis; bayesian hierarchical; participant data; model ... See more keywords
Calculating the power to examine treatment‐covariate interactions when planning an individual participant data meta‐analysis of randomized trials with a binary outcome
Sign Up to like & getrecommendations! Published in 2022 at "Statistics in Medicine"
DOI: 10.1002/sim.9538
Abstract: Before embarking on an individual participant data meta‐analysis (IPDMA) project, researchers and funders need assurance it is worth their time and cost. This should include consideration of how many studies are promising their IPD and,… read more here.
Keywords: participant data; individual participant; power; data meta ... See more keywords
[New applications for individual participant data meta-analyses of randomized trials].
Sign Up to like & getrecommendations! Published in 2017 at "Bulletin du cancer"
DOI: 10.1016/j.bulcan.2016.10.024
Abstract: Meta-analyses of randomized trials using individual-participant data, which represent the highest level of evidence for the evaluation of a treatment effect, are now used in different contexts in clinical research. This article aims at reviewing… read more here.
Keywords: meta analyses; new applications; analyses randomized; participant data ... See more keywords
Callosotomy affects performance IQ: A meta-analysis of individual participant data
Sign Up to like & getrecommendations! Published in 2018 at "Neuroscience Letters"
DOI: 10.1016/j.neulet.2017.11.040
Abstract: Morphometric neuroimaging studies on healthy adult individuals regularly report a positive association between intelligence test performance (IQ) and structural properties of the corpus callosum (CC). At the same time, studies examining the effect of callosotomy… read more here.
Keywords: surgery; analysis individual; callosotomy; performance ... See more keywords
Anterior Thoracic Spinal Cord Herniation: Surgical Treatment and Postoperative Course. An Individual Participant Data Meta-Analysis of 246 Cases.
Sign Up to like & getrecommendations! Published in 2019 at "World neurosurgery"
DOI: 10.1016/j.wneu.2018.11.229
Abstract: BACKGROUND Anterior thoracic spinal cord herniation (ATSCH) is a rare cause of progressive myelopathy. Early surgery is essential, but there is no agreement about the best surgical approach. OBJECTIVE To identify factors that determine surgical… read more here.
Keywords: analysis; anterior thoracic; individual participant; thoracic spinal ... See more keywords
The reciprocal relationship between alliance and early treatment symptoms: A two-stage individual participant data meta-analysis.
Sign Up to like & getrecommendations! Published in 2020 at "Journal of consulting and clinical psychology"
DOI: 10.1037/ccp0000594
Abstract: OBJECTIVE Even though the early alliance has been shown to robustly predict posttreatment outcomes, the question whether alliance leads to symptom reduction or symptom reduction leads to a better alliance remains unresolved. To better understand… read more here.
Keywords: data meta; alliance; meta; participant data ... See more keywords
An individual participant data meta-analysis on metabolomics profiles for obesity and insulin resistance in European children
Sign Up to like & getrecommendations! Published in 2019 at "Scientific Reports"
DOI: 10.1038/s41598-019-41449-x
Abstract: Childhood obesity prevalence is rising in countries worldwide. A variety of etiologic factors contribute to childhood obesity but little is known about underlying biochemical mechanisms. We performed an individual participant meta-analysis including 1,020 pre-pubertal children… read more here.
Keywords: obesity; homa; individual participant; meta analysis ... See more keywords
Individual participant data meta-analysis with mixed-effects transformation models.
Sign Up to like & getrecommendations! Published in 2021 at "Biostatistics"
DOI: 10.1093/biostatistics/kxab045
Abstract: One-stage meta-analysis of individual participant data (IPD) poses several statistical and computational challenges. For time-to-event outcomes, the approach requires the estimation of complicated nonlinear mixed-effects models that are flexible enough to realistically capture the most… read more here.
Keywords: participant data; transformation models; individual participant; mixed effects ... See more keywords
Blood pressure lowering treatment for prevention of cardiovascular events in patients with atrial fibrillation: an individual-participant data meta-analysis
Sign Up to like & getrecommendations! Published in 2020 at "European Heart Journal"
DOI: 10.1093/ehjci/ehaa946.0672
Abstract: Randomised evidence showing that pharmacological blood pressure (BP) lowering can reduce cardiovascular risk of patients with atrial fibrillation (AF) is limited. This study aimed to compare the effect of BP-lowering treatment on fatal and non-fatal… read more here.
Keywords: lowering treatment; events patients; treatment; cardiovascular events ... See more keywords