Detection of Glaucoma Progression in Individuals of African Descent Compared With Those of European Descent
Sign Up to like & getrecommendations! Published in 2018 at "JAMA Ophthalmology"
DOI: 10.1001/jamaophthalmol.2017.6836
Abstract: Importance Individuals of African descent have been reported to be at higher risk for becoming visually impaired from glaucoma compared with individuals of European descent. Objective To investigate racial differences in longitudinal visual field variability… read more here.
Keywords: compared european; european descent; individuals african; african descent ... See more keywords
APOL1 risk variants in individuals of African genetic ancestry drive endothelial cell defects that exacerbate sepsis.
Sign Up to like & getrecommendations! Published in 2021 at "Immunity"
DOI: 10.1016/j.immuni.2021.10.004
Abstract: The incidence and severity of sepsis is higher among individuals of African versus European ancestry. We found that genetic risk variants (RVs) in the trypanolytic factor apolipoprotein L1 (APOL1), present only in individuals of African… read more here.
Keywords: sepsis; individuals african; ancestry; apol1 ... See more keywords
Rare coding variants associated with blood pressure variation in 15 914 individuals of African ancestry
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Hypertension"
DOI: 10.1097/hjh.0000000000001319
Abstract: Objectives: Hypertension is a major risk factor for all cardiovascular diseases, especially among African Americans. This study focuses on identifying specific blood pressure (BP) genes using 15 914 individuals of African ancestry from eight cohorts (Africa… read more here.
Keywords: blood pressure; african ancestry; 914 individuals; individuals african ... See more keywords
Meta-Analysis and Multivariate GWAS Analyses in 77,850 Individuals of African Ancestry Identify Novel Variants Associated with Blood Pressure Traits
Sign Up to like & getrecommendations! Published in 2023 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms24032164
Abstract: High blood pressure (HBP) has been implicated as a major risk factor for cardiovascular diseases in several populations, including individuals of African ancestry. Despite the elevated burden of HBP-induced cardiovascular diseases in Africa and other… read more here.
Keywords: meta analysis; individuals african; analysis; african ancestry ... See more keywords