Differential Associations of Apolipoprotein E ε4 Genotype With Attentional Abilities Across the Life Span of Individuals With Down Syndrome
Sign Up to like & getrecommendations! Published in 2020 at "JAMA Network Open"
DOI: 10.1001/jamanetworkopen.2020.18221
Abstract: Key Points Question What are the associations between the Alzheimer disease risk allele apolipoprotein E (APOE) ε4 and attention across the life span of individuals with Down syndrome? Findings In a cross-sectional study including 80… read more here.
Keywords: individuals syndrome; span individuals; across life; life span ... See more keywords
Alzheimer Dementia Among Individuals With Down Syndrome
Sign Up to like & getrecommendations! Published in 2024 at "JAMA Network Open"
DOI: 10.1001/jamanetworkopen.2024.35018
Abstract: Key Points Question What is the incidence and prevalence of Alzheimer dementia in patients with Down syndrome using data from the US Medicare and Medicaid? Findings In this cohort study of 132 720 adults with Down… read more here.
Keywords: dementia; alzheimer dementia; among individuals; individuals syndrome ... See more keywords
Communication intervention for individuals with Down syndrome: Systematic review and meta-analysis
Sign Up to like & getrecommendations! Published in 2018 at "Developmental Neurorehabilitation"
DOI: 10.1080/17518423.2016.1212947
Abstract: ABSTRACT Objective: A systematic review was conducted to identify effective intervention strategies for communication in individuals with Down syndrome. Methods: We updated and extended previous reviews by examining: (1) participant characteristics; (2) study characteristics; (3)… read more here.
Keywords: individuals syndrome; systematic review; communication intervention;
Systematic Review of the Main Motor Scales for Clinical Assessment of Individuals with down Syndrome
Sign Up to like & getrecommendations! Published in 2019 at "Developmental Neurorehabilitation"
DOI: 10.1080/17518423.2019.1687598
Abstract: ABSTRACT Objective: The aim of the present review was to identify the motor scales currently used to assess individuals with Down Syndrome (DS). Method: PubMed, WOS and BVS databases were systematically searched to identify the… read more here.
Keywords: individuals syndrome; motor scales; systematic review; motor ... See more keywords
Blunted Exercise Pressor Reflex in Individuals with Down Syndrome
Sign Up to like & getrecommendations! Published in 2024 at "Physiology"
DOI: 10.1152/physiol.2024.39.s1.1236
Abstract: INTRODUCTION: Individuals with Down syndrome (DS) exhibit autonomic dysfunction, which contributes to reduced work capacity. The chemically sensitive component of the exercise pressor reflex, the metaboreflex, is responsible for exercise-induced sympathoexcitation and can be assessed… read more here.
Keywords: exercise pressor; physiology; pressor reflex; individuals syndrome ... See more keywords
Enhancing Consumer Skills in Individuals With Down Syndrome
Sign Up to like & getrecommendations! Published in 2025 at "Research on Social Work Practice"
DOI: 10.1177/10497315251359144
Abstract: Purpose: This study evaluated a father-focused family education program to enhance digital consumer skills in individuals with down syndrome. Method: A single-subject multiple probe design was used with four father–child dyads. Fathers received training on… read more here.
Keywords: enhancing consumer; individuals syndrome; consumer skills; skills individuals ... See more keywords
Charting the future: current and future directions in translational research for individuals with Down syndrome
Sign Up to like & getrecommendations! Published in 2025 at "Journal of Neurodevelopmental Disorders"
DOI: 10.1186/s11689-025-09630-8
Abstract: The most common genetic cause of intellectual and developmental disability is trisomy of human chromosome 21 (trisomy 21) or Down syndrome. Relative to the general population, individuals with Down syndrome heterogeneously experience atypical morphogenesis, a… read more here.
Keywords: charting future; current future; future current; individuals syndrome ... See more keywords
Alterations in intestinal microbiota and metabolites in individuals with Down syndrome and their correlation with inflammation and behavior disorders in mice
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Microbiology"
DOI: 10.3389/fmicb.2023.1016872
Abstract: The intestinal microbiota and fecal metabolome have been shown to play a vital role in human health, and can be affected by genetic and environmental factors. We found that individuals with Down syndrome (DS) had… read more here.
Keywords: inflammation behavior; intestinal microbiota; alterations intestinal; behavior disorders ... See more keywords
Swimmers with Down Syndrome Are Healthier and Physically Fit than Their Untrained Peers
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DOI: 10.3390/healthcare11040482
Abstract: While there are positive benefits from physical activity participation for individuals with Down syndrome, little is known about the effects of swimming training. The aim of this study was to compare the body composition and… read more here.
Keywords: swimmers syndrome; syndrome healthier; physically fit; healthier physically ... See more keywords
COVID-19 Vaccination of Individuals with Down Syndrome—Data from the Trisomy 21 Research Society Survey on Safety, Efficacy, and Factors Associated with the Decision to Be Vaccinated
Sign Up to like & getrecommendations! Published in 2022 at "Vaccines"
DOI: 10.3390/vaccines10040530
Abstract: Individuals with Down syndrome (DS) are among the groups with the highest risk for severe COVID-19. Better understanding of the efficacy and risks of COVID-19 vaccines for individuals with DS may help improve uptake of… read more here.
Keywords: survey; safety efficacy; vaccination; individuals syndrome ... See more keywords