Exploring Kinase Inhibition Properties of 9H-pyrimido[5,4-b]- and [4,5-b]indol-4-amine Derivatives
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DOI: 10.3390/ph13050089
Abstract: We previously highlighted the interest in 6,5,6-fused tricyclic analogues of 4-aminoquinazolines as kinase inhibitors in the micromolar to the nanomolar range of IC50 values. For the generation of chemical libraries, the formamide-mediated cyclization of the… read more here.
Keywords: amine derivatives; kinase inhibition; pyrimido indol; indol amine ... See more keywords