Ester-derivatized indoles as sensitive infrared probes for local environment
Sign Up to like & getrecommendations! Published in 2020 at "Chemical Physics Letters"
DOI: 10.1016/j.cplett.2020.137139
Abstract: Abstract Methyl indole-4-carboxylate emits around 450 nm with fairly long fluorescence lifetime, which makes it a promising fluorescent probe for protein local structure and dynamics. Plus, it can also be used as an IR probe to… read more here.
Keywords: ester derivatized; methyl indole; probe; derivatized indoles ... See more keywords
Enzymatic analysis of glucuronidation of synthetic cannabinoid 1-naphthyl 1-(4-fluorobenzyl)-1H-indole-3-carboxylate (FDU-PB-22)
Sign Up to like & getrecommendations! Published in 2019 at "Xenobiotica"
DOI: 10.1080/00498254.2019.1580403
Abstract: Abstract Recently, there has been a rise in abuse of synthetic cannabinoids (SCBs). The consumption of SCBs results in various effects and can induce toxic reactions, including paranoia, seizures, tachycardia and even death. 1-Naphthyl 1-(4-fluorobenzyl)-1H-indole-3-carboxylate… read more here.
Keywords: fluorobenzyl indole; glucuronidation; fdu; indole carboxylate ... See more keywords
Gut Microbiota-Derived Indole-3-Carboxylate Influences Mucosal Integrity and Immunity Through the Activation of the Aryl Hydrocarbon Receptors and Nutrient Transporters in Broiler Chickens Challenged With Eimeria maxima
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2022.867754
Abstract: Two studies were conducted to evaluate the effects of indole-3-carboxylate (ICOOH) as a postbiotic on maintaining intestinal homeostasis against avian coccidiosis. In the first study, an in vitro culture system was used to investigate the… read more here.
Keywords: indole carboxylate; broiler chickens; hydrocarbon receptors; integrity ... See more keywords
Design, Synthesis, and Antiproliferative Activity of New 5-Chloro-indole-2-carboxylate and Pyrrolo[3,4-b]indol-3-one Derivatives as Potent Inhibitors of EGFRT790M/BRAFV600E Pathways
Sign Up to like & getrecommendations! Published in 2023 at "Molecules"
DOI: 10.3390/molecules28031269
Abstract: Mutant EGFR/BRAF pathways are thought to be crucial targets for the development of anticancer drugs since they are over-activated in several malignancies. We present here the development of a novel series of 5-chloro-indole-2-carboxylate 3a–e, 4a–c… read more here.
Keywords: indole carboxylate; pyrrolo indol; carboxylate pyrrolo; chloro indole ... See more keywords