Indole-coumarin-thiadiazole hybrids: An appraisal of their MCF-7 cell growth inhibition, apoptotic, antimetastatic and computational Bcl-2 binding potential.
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DOI: 10.1016/j.ejmech.2017.05.032
Abstract: Cancer therapeutic potential of thiadiazole hybrids incorporating pharmacologically active indole and coumarin moieties have not been explored much. In the current investigation, three new thiadiazole hybrids with spacers of varying lengths linking indole and thiadiazole… read more here.
Keywords: bcl; indole coumarin; thiadiazole hybrids; apoptosis ... See more keywords