Reprogramming Escherichia coli for the production of prenylated indole diketopiperazine alkaloids
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DOI: 10.1038/s41598-019-45519-y
Abstract: Prenylated indole diketopiperazine (DKP) alkaloids are important bioactive molecules or their precursors. In the context of synthetic biology, efficient means for their biological production would increase their chemical diversification and the discovery of novel bioactive… read more here.
Keywords: production; indole diketopiperazine; escherichia coli; dkp alkaloids ... See more keywords
Bioactive Indole Diketopiperazine Alkaloids from the Marine Endophytic Fungus Aspergillus sp. YJ191021
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DOI: 10.3390/md19030157
Abstract: Six new prenylated indole diketopiperazine alkaloids, asperthrins A–F (1–6), along with eight known analogues (7–14), were isolated from the marine-derived endophytic fungus Aspergillus sp. YJ191021. Their planar structures and absolute configurations were elucidated by HR-ESI-MS,… read more here.
Keywords: endophytic fungus; diketopiperazine alkaloids; aspergillus yj191021; indole diketopiperazine ... See more keywords
Antibacterial Indole Diketopiperazine Alkaloids from the Deep-Sea Cold Seep-Derived Fungus Aspergillus chevalieri
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DOI: 10.3390/md21030195
Abstract: A large body of fungal secondary metabolites has been discovered to exhibit potent antibacterial activities with distinctive mechanisms and has the potential to be an untapped resource for drug discovery. Here, we describe the isolation… read more here.
Keywords: antibacterial indole; sea cold; indole diketopiperazine; deep sea ... See more keywords