Application of an activity-based receptor bioassay to investigate the in vitro activity of selected indole- and indazole-3-carboxamide-based synthetic cannabinoids at CB1 and CB2 receptors.
Sign Up to like & getrecommendations! Published in 2019 at "Drug testing and analysis"
DOI: 10.1002/dta.2517
Abstract: Synthetic cannabinoids (SCs) are the most chemically diverse group of new psychoactive substances. This group has been associated with several intoxications, many with fatal outcomes. Although advancements have been achieved in pharmacology, metabolism, and detection… read more here.
Keywords: synthetic cannabinoids; indole indazole; cb1 cb2; investigate vitro ... See more keywords
New indole and indazole derivatives as potential antimycobacterial agents
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DOI: 10.1007/s00044-019-02293-w
Abstract: AbstractThe study reports on the synthesis and in vitro assessment of the antimycobacterial activity of a series of new indole- and indazole-based aroylhydrazones evaluated against Mycobacterium tuberculosis H37Rv. Isoniazide and ethambutol were used as reference… read more here.
Keywords: indole indazole; antimycobacterial activity; new indole; indazole derivatives ... See more keywords
Analysis of indole and indazole amides synthetic cannabinoids by differential Raman spectroscopy based on ANN
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DOI: 10.1111/1556-4029.15133
Abstract: A simple, rapid, accurate, and non‐destructive method was developed for the determination of cannabinoids, combining principal component analysis and multi‐layer perceptron neural network to classify indole and indazole amide synthetic cannabinoids. Under the experimental conditions… read more here.
Keywords: indole indazole; classification; differential raman; spectroscopy ... See more keywords