Advancements on Small Molecule PROTACs Containing an Indole/Spiro-fused Oxoindole Scaffolds: An Emerging Degrader Targeting Cancers.
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DOI: 10.2174/1871520622666220509175305
Abstract: Indole and spiro-fused oxoindole frameworks widely exist in a variety of natural bioactive products, pharmaceuticals and drug candidates, featuring unique functions in the regulation of proliferation, infiltration, and metastasis of cancer cells. In recent years,… read more here.
Keywords: small molecule; indole spiro; spiro fused; fused oxoindole ... See more keywords